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Typhon AI: The Ultimate 8x GPU Powerhouse for Enterprise AI & HPC

Accelerate breakthroughs with AMD EPYC™ 9005 CPUs, NVIDIA® MGX™ architecture, and next-gen PCIe 5.0 connectivity — purpose-built for AI, ML, and high-performance computing at scale.

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Next-generation infrastructure powered by AMD EPYC™ & NVIDIA® MGX™  
GPU PowerUp to 8× NVIDIA® Blackwell RTX Pro GPUs (dual-slot, active or passive)
CPUAMD EPYC™ 9005 Series (3nm, DDR5 DIMMs, PCIe 5.0)
Form FactorHigh-density 4U rackmount server
ScalabilityNVIDIA® NVLink® Bridge and AMD Infinity Fabric™ Link support
ConnectivityBroadcom PEX89000 PCIe 5.0 switches, 1,024Gbps (128GBps) per port
MaintenanceTool-less chassis design with complete disassembly for serviceability
ManagementASUS ASMB11-iKVM remote management + ASUS Control Center (ACC)
SecurityTrusted Platform Module (TPM) 2.0 with regular firmware updates

High-Density Compute, Purpose-Built for AI & HPC ​

Typhon AI is a high-density 4U compute server designed for organizations pushing the limits of AI, ML, and HPC. 

With support for up to eight dual-slot NVIDIA® Blackwell RTX Pro GPUs and powered by AMD EPYC™ 9005 processors, it delivers unmatched parallel processing power, faster GPU interconnects, and higher-bandwidth fabric. Flexible scaling options — including NVIDIA® NVLink® Bridge and AMD Infinity Fabric™ Link — make Typhon AI ideal for accelerating enterprise AI workloads, complex simulations, and next-generation research.

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Powered by AMD EPYC™ 9005 processors, ESC8000A-E13P delivers exceptional performance, featuring top-tier GPUs, faster GPU interconnects, and higher-bandwidth fabric. This powerhouse server supports up to eight dual-slot GPUs (up to 600W each), either active or passive, and offers flexible scalability with options for NVIDIA® NVLink® Bridge or AMD Infinity Fabric™ Link. This configuration allows seamless scaling and performance enhancement, making ESC8000A-E13P an ideal choice for tackling the most demanding enterprise AI and HPC tasks.  

ESC8000A-E13P takes AI infrastructure to the next level by leveraging NVIDIA® MGX™, an open and flexible reference design that ensures future-proof compatibility. With its innovative modular architecture offering up to 160 customizable configurations, clients can easily tailor their solutions to meet specific AI and high-performance computing needs. MGX sets a new industry benchmark for modular server design, enhancing ROI and slashing time to market — empowering businesses to stay ahead in the fast-evolving AI landscape.  

The AMD EPYC™ 9005 series takes AMD’s legacy of x86 architecture innovation to new heights, leveraging cutting-edge 3nm technology for record-breaking performance. With the introduction of high-performance DDR5 DIMMs and blazing-fast PCIe 5.0 I/O, EPYC™ 9005 CPUs are engineered to handle the most demanding workloads. In a dual-socket configuration, the platform delivers up to 192 Zen 5c cores and 128 PCIe 5.0 lanes, making it purpose-built for memory-hungry AI-driven data centers, machine learning, high-performance computing, and large in-memory simulations  

This server features the latest Broadcom PEX89000 series of switches, supporting up to 1,024Gbps (128GBps) of raw bandwidth per port (x16) to create high-availability hyper-scale systems. It uses the PCI Express 5.0 bus to empower communication between in-rack hosts and endpoints. With multiple PCIe Gen5 expansion slots for NIC and BlueField-3 cards, Typhon AI simplifies connectivity while providing the highest PCIe-switching performance available for data center servers, storage, and networks.

Designed for easy maintenance with a refined mechanical structure, ESC8000A-E13P allows the entire system to be disassembled completely without tools.

  • Tool-less PCIe card removal and quick installation for rapid upgrades
  • Hot-swap support for up to 8 × 2.5” NVMe drives

Remote Server Management: ASUS ASMB11-iKVM, built on the ASPEED 2600 chipset with AMI MegaRAC SP-X, provides full out-of-band access through WebGUI, IPMI, and Redfish® API.

Streamlined IT Operations: ASUS Control Center (ACC) enables centralized hardware/software monitoring, remote BIOS configurations, diagnostics, and enhanced security with hotfix updates — simplifying IT management across infrastructure.

Typhon AI supports Trusted Platform Module 2.0 (TPM 2.0) to secure hardware with cryptographic keys. Regular firmware updates help protect against vulnerabilities, ensuring enterprise-grade reliability for mission-critical environments.

Effortless maintenance with a toolless design for speed and simplicity

Designed for easy maintenance with a refined mechanical structure, ESC8000A-E13P allows the entire machine to be disassembled completely without tools.

Streamline IT operations via a single dashboard

ASUS Control Center (ACC) is remote IT-management software application designed for monitoring hardware and software IT assets and inventory status, and enabling seamless remote BIOS configurations and updates, efficient IT diagnostics and troubleshooting and enhanced security with hotfix updates — allowing easier server management for any IT infrastructure.

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Ready to Power Your Next Breakthrough?

Typhon AI is built for enterprises, research labs, and data centers that demand uncompromising GPU performance and scalable infrastructure. Configure your system today and accelerate your most demanding AI, ML, and HPC workloads.

EDU Pricing: Save $11,200